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1

Strukturbasis und Stereochemie der Triscatecholat-Siderophor- Bindung durch FeuA

Florian Peuckert, Marcus Miethke, Alexander G. Albrecht, Lars-Oliver Essen, Mohamed A. Marahiel

Journal:

Angewandte Chemie

Year:

2009

Language:

german

File:

PDF, 650 KB

german, 2009

2

Direkte Identifizierung eines Siderophor-Importproteins durch synthetische Petrobactinliganden

Nikolas Bugdahn, Florian Peuckert, Alexander G. Albrecht, Dr. Marcus Miethke, Prof. Dr. Mohamed A. Marahiel, Dr. Markus Oberthür

Journal:

Angewandte Chemie

Year:

2010

Language:

german

File:

PDF, 378 KB

german, 2010

3

Structural Basis and Stereochemistry of Triscatecholate Siderophore Binding by FeuA

Florian Peuckert, Marcus Miethke, Alexander G. Albrecht, Lars-Oliver Essen, Mohamed A. Marahiel

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 647 KB

english, 2009

4

Direct Identification of a Siderophore Import Protein Using Synthetic Petrobactin Ligands

Nikolas Bugdahn, Florian Peuckert, Alexander G. Albrecht, Dr. Marcus Miethke, Prof. Dr. Mohamed A. Marahiel, Dr. Markus Oberthür

Journal:

Angewandte Chemie International Edition

Year:

2010

Language:

english

File:

PDF, 394 KB

english, 2010

5

The Frataxin Homologue Fra Plays a Key Role in Intracellular Iron Channeling in Bacillus subtilis

Alexander G. Albrecht, Hannes Landmann, David Nette, Dr. Olaf Burghaus, Dr. Florian Peuckert, Prof. Dr. Andreas Seubert, Dr. Marcus Miethke, Prof. Dr. Mohamed A. Marahiel

Journal:

Year:

2011

Language:

english

File:

PDF, 1.85 MB

english, 2011

6

The Siderophore Binding Protein FeuA Shows Limited Promiscuity toward Exogenous Triscatecholates

Florian Peuckert, Ana Laura Ramos-Vega, Marcus Miethke, Clemens J. Schwörer, Alexander G. Albrecht, Markus Oberthür, Mohamed A. Marahiel

Journal:

Chemistry & Biology

Year:

2011

Language:

english

File:

PDF, 1.64 MB

english, 2011

7

Nitric oxide synthase-1 is enriched in fast-twitch oxidative myofibers

Gerit Planitzer, Alexander Miethke, Oliver Baum

Journal:

Cell and Tissue Research

Year:

2001

Language:

english

File:

PDF, 171 KB

english, 2001

8

Regulatory T cells control the CD8 adaptive immune response at the time of ductal obstruction in experimental biliary atresia

Celine S. Lages, Julia Simmons, Claire A. Chougnet, Alexander G. Miethke

Journal:

Year:

2012

Language:

english

File:

PDF, 1.56 MB

english, 2012

9

The Role of Regulatory T Cells in the Pathogenesis of Experimental Biliary Atresia

Alexander Miethke, Pranavkumar Shivakumar, Jorge Bezerra

Journal:

Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 44 KB

english, 2007

10

Mechanistic characterization of sulfur transfer from cysteine desulfurase SufS to the iron–sulfur scaffold SufU in Bacillus subtilis

Alexander G. Albrecht, Florian Peuckert, Hannes Landmann, Marcus Miethke, Andreas Seubert, Mohamed A. Marahiel

Journal:

Year:

2011

Language:

english

File:

PDF, 940 KB

english, 2011

11

Post-natal paucity of regulatory T cells and control of NK cell activation in experimental biliary atresia

Alexander G. Miethke, Vijay Saxena, Pranavkumar Shivakumar, Gregg E. Sabla, Julia Simmons, Claire A. Chougnet

Journal:

Journal of Hepatology

Year:

2010

Language:

english

File:

PDF, 1.22 MB

english, 2010

12

The specificity of the histochemical NADPH diaphorase reaction for nitric oxide synthase-1 in skeletal muscles is increased in the presence of urea

Oliver Baum, Alexander Miethke, Achim Wöckel, Gregor Willerding, Gerit Planitzer

Journal:

Acta Histochemica

Year:

2002

Language:

english

File:

PDF, 575 KB

english, 2002

13

Localization of NOS-1 in the sarcolemma region of a subpopulation of atrial cardiomyocytes including myoendocrine cells and NOS-3 in vascular and endocardial endothelial cells of the rat heart

Alexander Miethke, Markus Feussner, Gerit Planitzer, Heidrun Richter, Martina Gutsmann, Reinhart Gossrau

Journal:

Acta Histochemica

Year:

2003

Language:

english

File:

PDF, 299 KB

english, 2003

14

Fishing for Biliary Atresia Susceptibility Genes

Miethke, Alexander G., Huppert, Stacey S.

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 494 KB

english, 2013

15

847 The Types of Inflammatory Bowel Disease (IBD) Predispose to Distinct Clinical Phenotypes of Primary Sclerosing Cholangitis (PSC) in Children

Jones, Keaton R., Bufler, Philip, Miethke, Alexander G.

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 237 KB

english, 2014

16

Medical Status of 219 Children with Biliary Atresia Surviving Long-Term with Their Native Livers: Results from a North American Multicenter Consortium

Ng, Vicky Lee, Haber, Barbara H., Magee, John C., Miethke, Alexander, Murray, Karen F., Michail, Sonia, Karpen, Saul J., Kerkar, Nanda, Molleston, Jean P., Romero, Rene, Rosenthal, Philip, Schwarz, Ka

Journal:

The Journal of Pediatrics

Year:

2014

Language:

english

File:

PDF, 474 KB

english, 2014

17

Pathogenesis of biliary atresia: defining biology to understand clinical phenotypes

Asai, Akihiro, Miethke, Alexander, Bezerra, Jorge A.

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Year:

2015

Language:

english

File:

PDF, 503 KB

english, 2015

18

Predictors of Outcome in Patients with Normal-Pressure Hydrocephalus

Meier, Ullrich, K&ouml, nig, Alexander, Miethke, Christoph

Journal:

European Neurology

Year:

2004

Language:

english

File:

PDF, 196 KB

english, 2004

19

Analysis of Gene Mutations in Children With Cholestasis of Undefined Etiology

Matte, Ursula, Mourya, Reena, Miethke, Alexander, Liu, Cong, Kauffmann, Gregory, Moyer, Katie, Zhang, Kejian, Bezerra, Jorge A

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Year:

2010

Language:

english

File:

PDF, 199 KB

english, 2010

20

Pharmacological inhibition of apical sodium-dependent bile acid transporter changes bile composition and blocks progression of sclerosing cholangitis in multidrug resistance 2 knockout mice

Miethke, Alexander G., Zhang, Wujuan, Simmons, Julia, Taylor, Amy E., Shi, Tiffany, Shanmukhappa, Shiva Kumar, Karns, Rebekah, White, Shana, Jegga, Anil G., Lages, Celine S., Nkinin, Stephenson, Kelle

Journal:

Year:

2016

Language:

english

File:

PDF, 1.29 MB

english, 2016

21

Management of Stage 4S Composite Neuroblastoma With a MYCN-amplified Nodule

Bishop, Michael W., Yin, Hong, Shimada, Hiroyuki, Towbin, Alexander J., Miethke, Alexander, Weiss, Brian

Journal:

Journal of Pediatric Hematology/Oncology

Year:

2014

Language:

english

File:

PDF, 376 KB

english, 2014

22

Increased frequency of double and triple heterozygous gene variants in children with intrahepatic cholestasis

Goldschmidt, Monique L., Mourya, Reena, Connor, Jessica, Dexheimer, Phillip, Karns, Rebekah, Miethke, Alexander, Sheridan, Rachel, Zhang, Kejian, Bezerra, Jorge A.

Journal:

Hepatology Research

Year:

2016

Language:

english

File:

PDF, 850 KB

english, 2016

23

A Case of Salicylate Intoxication Complicated by Coagulopathy, Pulmonary Edema, and Pancreatitis

Ayalon, Itay, Alder, Matthew Noble, Langner, Travis Ryan, Hafberg, Einar Thor, Miethke, Alexander Gerhard, Kaplan, Jennifer Melissa

Journal:

American Journal of Therapeutics

Year:

2016

Language:

english

File:

PDF, 111 KB

english, 2016

24

Evaluation of the Child With Suspected Mitochondrial Liver Disease

Molleston, Jean P., Sokol, Ronald J., Karnsakul, Wikrom, Miethke, Alexander, Horslen, Simon, Magee, John C., Romero, René, Squires, Robert H., Van Hove, Johan L.K.

Journal:

Journal of Pediatric Gastroenterology & Nutrition

Year:

2013

Language:

english

File:

PDF, 356 KB

english, 2013

25

Multiple Dysplastic Liver Nodules in PFIC2 Underscore Risk for Neoplasia Associated With Functional BSEP Deficiency

Sheridan, Rachel M., Gupta, Anita, Miethke, Alexander, Knisely, Alexander S., Bove, Kevin E.

Journal:

American Journal of Surgical Pathology

Year:

2012

Language:

english

File:

PDF, 160 KB

english, 2012

26

Morphologic Findings in Progressive Familial Intrahepatic Cholestasis 2 (PFIC2)

Evason, Kimberley, Bove, Kevin E., Finegold, Milton J., Knisely, A.S., Rhee, Sue, Rosenthal, Philip, Miethke, Alexander G., Karpen, Saul J., Ferrell, Linda D., Kim, Grace E.

Journal:

American Journal of Surgical Pathology

Year:

2011

Language:

english

File:

PDF, 822 KB

english, 2011

27

Zebrafish abcb11b mutant reveals novel strategies to restore bile excretion impaired by bile salt export pump deficiency

Ellis, Jillian L., Bove, Kevin E., Schuetz, Erin G., Leino, Daniel, Valencia, C. Alexander, Schuetz, John D., Miethke, Alexander, Yin, Chunyue

Journal:

Year:

2017

Language:

english

File:

PDF, 2.08 MB

english, 2017

28

Placebo-Controlled Randomized Trial of an Intestinal Bile Salt Transport Inhibitor for Pruritus in Alagille Syndrome

Shneider, Benjamin L., Spino, Cathie, Kamath, Binita M., Magee, John C., Bass, Lee M., Setchell, Kenneth D., Miethke, Alexander, Molleston, Jean P., Mack, Cara L., Squires, Robert H., Murray, Karen F.

Journal:

Hepatology Communications

Year:

2018

Language:

english

File:

PDF, 756 KB

english, 2018

29

Diagnostic performance of quantitative magnetic resonance imaging biomarkers for predicting portal hypertension in children and young adults with autoimmune liver disease

Dillman, Jonathan R., Serai, Suraj D., Trout, Andrew T., Singh, Ruchi, Tkach, Jean A., Taylor, Amy E., Blaxall, Burns C., Fei, Lin, Miethke, Alexander G.

Journal:

Pediatric Radiology

Year:

2019

Language:

english

File:

PDF, 4.50 MB

english, 2019

30

Rapid susceptibility testing of multi-drug resistant Escherichia coli and Klebsiella by glucose metabolization monitoring

Kittel, Maximilian, Findeisen, Peter, Ghebremedhin, Beniam, Miethke, Thomas, Grundt, Alexander, Ahmad-Nejad, Parviz, Neumaier, Michael

Journal:

Clinical Chemistry and Laboratory Medicine

Year:

2019

Language:

english

File:

PDF, 623 KB

english, 2019

31

SAT-376-Bile acids induce STAT3 and repress FOXP3 expression in hepatic CD4 lymphocytes under cholestatic conditions

Kudira, Ramesh, Silva-Lages, Celine, Taylor, Amy, Shi, Tiffany, Karns, Rebekah, Mulen, Mary, Zhang, Wujuan, Setchell, Kenneth, Miethke, Alexander

Journal:

Journal of Hepatology

Year:

2019

Language:

english

File:

PDF, 128 KB

english, 2019

32

Differentiating pediatric autoimmune liver diseases by quantitative magnetic resonance cholangiopancreatography

Gilligan, Leah A., Trout, Andrew T., Lam, Simon, Singh, Ruchi, Tkach, Jean A., Serai, Suraj D., Miethke, Alexander G., Dillman, Jonathan R.

Journal:

Abdominal Radiology

Year:

2019

Language:

english

File:

PDF, 963 KB

english, 2019

33

GS-15-Deficiency of the ABC transporter ABCC12/MRP9 is associated with chronic cholestasis syndromes and causes bile duct paucity in zebrafish and mouse model organisms

Xu, Lingfen, Pham, Duc Hung, Shi, Tiffany, Ellis, Jillian, Mulen, Mary, Valencia, Alexander, Mohanty, Sujit, Wali, Sami, Miethke, Alexander, Yin, Chunyue

Journal:

Journal of Hepatology

Year:

2019

Language:

english

File:

PDF, 855 KB

english, 2019

34

THU-016-Loss of signaling through the G-protein coupled bile acid receptor Tgr5 confers protection from fibrosis in the progressive cholangiopathy of Mdr2-/- mice

Matuschek, Nelson, Kudira, Ramesh, Mulen, Mary, Miethke, Alexander

Journal:

Journal of Hepatology

Year:

2019

Language:

english

File:

PDF, 61 KB

english, 2019

35

Evaluation of a change in CMV prevention strategy following pediatric solid organ transplantation

Pangonis, Scott, Paulsen, Grant, Andersen, Heidi, Flores, Francisco, Miethke, Alexander, Peters, Anna, Kocoshis, Samuel, Lazear, Danielle, Garr, BreAnn, Schecter, Marc, Chin, Clifford, Hemmelgarn, Tri

Journal:

Transplant Infectious Disease

Year:

2019

File:

PDF, 12.55 MB

2019

36

Lipopolysaccharide Reverses Hepatic Stellate Cell Activation via Modulation of cMyb, SMADs and C/EBP Transcription Factors

Sharma, Akanksha, Verma, Alok K., Kofron, Matthew, Kudira, Ramesh, Miethke, Alexander, Wu, Tong, Wang, Jiang, Gandhi, Chandrashekhar R

Journal:

Year:

2020

File:

PDF, 16.41 MB

2020

37

Four biomarkers linked to activation of CD8+ lymphocytes predict clinical outcomes in pediatric acute liver failure

Leonis, Mike A., Miethke, Alexander G., Fei, Lin, Maynor, Sean, Chapin, Catherine A., Bleesing, Jacob J.H., Alonso, Estella M., Squires, Robert H.

Journal:

Year:

2020

File:

PDF, 15.30 MB

2020

38

Relationship between magnetic resonance imaging spleen T1 relaxation and other radiologic and clinical biomarkers of liver fibrosis in children and young adults with autoimmune liver disease

Dillman, Jonathan R., Tkach, Jean A., Gandhi, Deep, Singh, Ruchi, Miethke, Alexander G., Jayaswal, Arun, Trout, Andrew T.

Journal:

Abdominal Radiology

Year:

2020

File:

PDF, 941 KB

2020

39

Comparison of liver T1 relaxation times without and with iron correction in pediatric autoimmune liver disease

Dillman, Jonathan R., Serai, Suraj D., Miethke, Alexander G., Singh, Ruchi, Tkach, Jean A., Trout, Andrew T.

Journal:

Pediatric Radiology

Year:

2020

File:

PDF, 848 KB

2020

40

Association between liver diffusion-weighted imaging apparent diffusion coefficient values and other measures of liver disease in pediatric autoimmune liver disease patients

Abu Ata, Nadeen, Dillman, Jonathan R., Gandhi, Deep B., Dudley, Jonathan A., Trout, Andrew T., Miethke, Alexander G.

Journal:

Abdominal Radiology

Year:

2020

File:

PDF, 722 KB

2020

41

Unraveling the Relationship Between Itching, Scratch Scales, and Biomarkers in Children With A lagille Syndrome

Kamath, Binita M., Spino, Cathie, McLain, Richard, Magee, John C., Fredericks, Emily M., Setchell, Kenneth D., Miethke, Alexander, Molleston, Jean P., Mack, Cara L., Squires, Robert H., Alonso, Estell

Journal:

Hepatology Communications

Year:

2020

File:

PDF, 235 KB

2020

42

A 4âYearâOld Child with Digital Clubbing

Schultz, Katherine, Divanovic, Allison, Towe, Christopher, Miethke, Alexander, Wusik, Katie, Hammill, Adrienne, Brunner, Hermine

Journal:

Arthritis Care & Research

Year:

2020

File:

PDF, 9.03 MB

2020

43

FXR agonists repress innate and adaptive effector cytokine production in primary sclerosing cholangitis

Malik, Astha, Matuschek, Louis, Shi, Tiffany, Mulen, Mary, Kudira, Ramesh, Singh, Ruchi, Maynor, Mr. Sean, Wagner, Brandee, Miethke, Alexander

Journal:

Journal of Hepatology

Year:

2020

File:

PDF, 175 KB

2020

44

Upregulation of hepatic TH17 response is associated with large duct disease and advanced hepatic fibrosis in pediatric autoimmune liver disease

Lam, Simon, Osuji, Immaculeta, vom Hofe, Annika Yang, Dillman, Jonathan, Sharma, Divya, Singh, Ruchi, Karns, Rebekah, Miethke, Alexander

Journal:

Journal of Hepatology

Year:

2020

File:

PDF, 268 KB

2020

45

Serum bile acid control in long-term maralixibat-treated patients is associated with native liver survival in children with progressive familial intrahepatic cholestasis due to bile salt export pump deficiency

Thompson, Richard, Kelly, Deirdre, Miethke, Alexander, Rajwal, Sanjay, Soufi, Nisreen, Jankowska, Irena, Mack, Cara, Lachaux, Alain, Jaecklin, Thomas, Vig, Pamela, Wardle, Andrew, Squires, Robert, Loo

Journal:

Journal of Hepatology

Year:

2020

File:

PDF, 61 KB

2020

46

Natural Course of Pediatric Portal Hypertension

Kassam, AlâFaraaz, Goddard, Gillian R., Johnston, Michael E., Cortez, Alexander R., Trout, Andrew T., Jenkins, Todd M., Miethke, Alexander G., Campbell, Kathleen M., Bezerra, Jorge A., Balistreri, W

Journal:

Hepatology Communications

Year:

2020

File:

PDF, 180 KB

2020

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